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 Biography   Marc G. Caron, Ph.D. James B. Duke Professor of Cell Biology Duke University Dr. Caron studies the mechanisms of action and regulation of hormones and neurotransmitters and how they might underlie nervous-system disorders such as schizophrenia, Parkinson's disease, attention-deficit hyperactivity disorders, mood disorders, addiction and Alzheimer’s disease. His laboratory uses biochemical, molecular-biological and gene-targeting approaches to explore these questions in animal models. He is a member of Duke University’s Institute for Genome Sciences and Policy, an inter-national group working to accelerate the identification of genes responsible for diseases. Recently, Dr. Caron and his Duke colleagues announced the discovery of a protein that, when defective, appears to contribute to memory loss. Mice engineered to have this defect show symptoms resembling those of Alzheimer’s disease. The protein affects the functioning of acetylcholine, a neurotransmitter essential to memory and other basic activities. His team now plans to use the mice to learn more about basic brain circuitry and as a possible aid to developing better ways to alleviate symptoms of Alzheimer’s disease. Dr. Caron joined NARSAD’s Scientific Council in 2000. He received a NARSAD Distinguished Investigator Award in 2005. |
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