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Biography

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Jonathan D. Cohen, M.D., Ph.D.
Eugene Higgins Professor of Psychology
Director, Princeton Neuroscience Institute
Princeton University

Professor of Psychiatry
University of Pittsburgh

One of the fundamental mysteries of neuroscience is how the capacity for coordinated, purposeful behavior arises from the distributed activity of many billions of neurons in the brain. Research in Dr. Cohen’s laboratory focuses on the neurobiological mechanisms underlying cognitive control and their disturbance in psychiatric disorders such as schizophrenia and depression.

Cognitive control is the ability to guide attention, thought and action in accord with goals or intentions. The mechanisms by which cognitive control influences, for example, attentional effects in sensory processing, goal-directed sequencing of motor output and the like; and the brain structures upon which these functions depend, such as the prefrontal cortex, anterior cingulate cortex, basal ganglia and brain-stem neuromodulatory systems, are still poorly understood. Dr. Cohen and his colleagues are working to develop and test explicit hypotheses that will help to explain how these mechanisms work.

Dr. Cohen joined NARSAD’s Scientific Council in 1997. He received a NARSAD Independent Investigator Award in 1997.
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