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![]() Mark A. Geyer, Ph.D. Professor of Psychiatry and Neurosciences Vice Chair, Scientific Affairs, Department of Psychiatry University of California, San Diego Dr. Geyer’s laboratory uses behavioral measures and psychopharmacological manipulations in rodents and humans to examine the roles in behavior of monoamines (molecules that include neurotransmitters) in order to develop animal models of human drug effects and explore information-processing deficits in schizophrenia, bipolar disorder and anxiety disorders. He applies measures of behaviors that are abnormal in psychiatric patients and mimicked in rodents through pharmacological, developmental and genetic manipulations. He also uses a Behavioral Pattern Monitor in rats, mice and patients to provide translational multivariate assessments of spatiotemporal patterns of exploratory behavior, including nonlinear dynamical measures of behavioral organization. Dr. Geyer’s recent research focuses on characterizations of knock-out mice, in which specific genes have been inactivated, including mice lacking receptor subtypes for dopamine, glutamate, serotonin and corticotropin-releasing factor neurotransmitters that play central roles in neurological and psychiatric disorders. He also directs the Neuropsychopharmacology Unit of the Veterans Administration Mental Illness Research, Clinical and Education Center, and has been centrally involved in the National Institute of Mental Health-funded MATRICS and TURNS Programs, focused on treatments for cognitive deficits in schizophrenia. Dr. Geyer joined NARSAD’s Scientific Council in 2001 and received a NARSAD Distinguished Investigator Award in 1996. |
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