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Low Birth Weight and Childhood Abuse Linked to Later Psychological Problems
But intervention may avert future troubles


(Great Neck, NY - ) — Children born with low birth weight (LBW) who subsequently suffer abuse are substantially more likely to develop psychological problems such as depression and social dysfunction during their adolescence and adulthood, according to a study at Mount Sinai School of Medicine (MSSM) led by a NARSAD-supported scientist.

The study, which appeared in the February 5, 2007, issue of The Archives of Pediatric & Adolescent Medicine, is the first to investigate the possible interaction between LBW and later adversity.

According to the Center for Disease Control (CDC), the percentage of infants born LBW (less than 2,500 grams) has risen 16 percent since 1990. LBW is a major public health problem in the United States, contributing substantially to both infant mortality and to childhood physical impairment.

To examine the possible conjoined effects of LBW and child abuse on adaptation and on the development of psychiatric and medical problems, the researchers looked at data from the John Hopkins Collaborative Perinatal Study, an epidemiologic study that followed a random sample of mothers and their children from pregnancy for more than 30 years. They compared outcomes in the transition to adulthood among four groups of children: those with LBW and childhood abuse, those with LBW alone, those with childhood abuse alone, and those with neither.

The researchers found that participants with both LBW and subsequent child abuse, relative to those with neither risk factor, were at a substantially elevated risk of developing psychological problems: a factor of nearly 10 for depression; nearly 9 for social dysfunction, and over 4 for somatization. However, these youths were not at an elevated risk for developing medical problems in adulthood.

Those who were abused were more likely to be delinquent, suspended from school, or needing to repeat a school grade during adolescence. They were also more likely to have problems in adulthood, regardless of LBW status. For those with LBW alone, the prevalence of those problems was comparable to that of those without either risk factor.

“The number of children born with low birth weight is steadily increasing in the country,” said Yoko Nomura, Ph.D., M.P.H, Assistant Professor of Psychiatry at Mount Sinai School of Medicine and lead investigator of the study. Dr. Nomura is a recipient of a NARSAD 2004 Young Investigator Grant. ” These findings suggest children faced with the adversity of low birth weight and subsequent child abuse had substantially poorer outcomes than children facing either adversity alone in various areas of their life.”

“The good news is that by offering preventative mental health services to mothers with LBW, and monitoring LBW children to provide early intervention, together we can protect such children from subsequent adversity such as abuse,” noted Claude M. Chemtob, Ph.D., Clinical Professor of Psychiatry and Pediatrics and one of the study investigators.

The study was supported by grants from the National Institute of Mental Health (NIHM) and the Erna Reich Fund of the UJA Federation of New York, and a Young Investigator Award from the National Alliance for Research on Schizophrenia and Depression (NARSAD).

Mount Sinai School of Medicine gave NARSAD: The Mental Health Research Association permission to adapt their release on this news story.

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