Project Summary

Caleb M. Adler, M.D. (Young Investigator 2000) of Psychiatric Professional Service, Inc., is investigating brain abnormalities that may underlie bipolar disorder.  Previous studies have demonstrated that patients with bipolar disorder have an impairment in the ability to distinguish one emotion from another.  In this study, Dr. Adler will examine brain activity in recovered bipolar patients, and healthy volunteers, while they are performing tasks of affect discrimination and facial recognition.  A recently developed technique, called functional magnetic resonance imaging (fori) will be used to examine brain activation in response to the different tasks.  The effects of medication on brain activation will also be examined.  This study may represent an important step toward identifying which brain regions are not functioning properly in patients with bipolar disorder.

Program Area: MOOD DISORDERS\Bipolar

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