Project Summary

Daniel Aeschbach, Ph.D. (Young Investigator 2003) of Brigham and Women's Hospital, hypothesizes that restoration of normal waking functions may depend on the intensity (i.e. depth of non-rapid-eye-movement or non-REM) sleep. Deep non-REM sleep, also called slow wave sleep, may be particularly important for waking functions that involve the brain's prefrontal cortex.   Experimental suppression of slow wave sleep may affect cerebral functions during subsequent wakefulness. This study may help depressed patients in that slow wave sleep suppression may help prolong the beneficial effects of total sleep deprivation on mood.

Program Area: MOOD DISORDERS\Depression (Unipolar)

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