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Ana M. Carneiro, Ph.D. (Young Investigator 2007) of Vanderbilt University Medical Center, plans to study two protein molecules that are present in platelets – one that activates the platelets to form blood clots, the other to control levels of serotonin both in the blood and in the brain, and is also the main target of antidepressant drugs. When these two proteins bind together, there is an indication that there might be a biological link between these molecules in terms of risk for both cardiovascular and neuropsychiatric disorders. Dr. Carneiro’s study suggests a common molecular link in the pathophysiology of depression and heart attacks that could explain the increased risks observed in the population. Program Area: MOOD DISORDERS\Mood Disorders (General) |
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