Project Summary

Heidi E.W. Day, Ph.D. (Young Investigator 2007) of the University of Colorado, Boulder, will use a rodent-based model to further investigate the effect of voluntary exercise (wheel running) on responses to mild stress. Dr. Day hypothesizes changes in the brain will occur as a consequence of long term voluntary exercise and 2) these changes will diminish various responses to a mild acute stress. The use of this specific model, combined with different stress response systems, is a strategic choice which will ultimately help in the determination of brain regions involved in the stress reducing effects of exercise, with clinical implications for both prevention and treatment of depressive and anxiety disorders.

Program Area: MULTIPLE FOCUS\Anxiety Disorders/Mood Disorders

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