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 Project Summary  Herbert M. Lachman, M.D. (Independent Investigator 2000) of Albert Einstein College of Medicine of Yeshiva University, will analyze all brain expressed genes on chromosome 22q11 in order to identify a gene that increases susceptibility to bipolar disorder. Previous work has demonstrated that velocardiofacial syndrome, caused by a deletion on chromosome 22, is associated with a variety of psychiatric outcomes, including bipolar disorder. This work will capitalize on the recent publication of the entire chromosome 22 DNA sequence. Dr. Lachman will attempt to identify several candidate genes on chromosome 22q11 for mutations that underlie the vulnerability to develop bipolar disorder. The identification of genes for bipolar disorder has important promise for prevention, and unraveling the pathogenesis of this illness. Program Area: MOOD DISORDERS\Bipolar |
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 Colleen Ann McClung, Ph.D., UT Southwestern Medical Center at Dallas, 2005 & 2007 Young Investigator Latest News from NARSAD
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