Project Summary

Belinda Lennox, BM, BS, MRCPsych DM (Young Investigator 2003) of Addenbrookes Hospital, previously showed that patients with mania demonstrate abnormalities in the brain areas involved in facial emotion recognition.  She now proposes to expand this work using functional magnetic resonance imaging (fMRI) technology to follow subjects with mania over time, and scan them at various stages of illness.  Dr. Lennox will examine how the brain areas involved in emotion processing change over the course of illness, and directly compare brain activation in the same subjects while performing the same task across various mood states (i.e. recovery, mania, depression).  This work will demonstrate whether mania and depression are abnormalities of the same neural circuitry, or if separate systems are involved, and if these abnormalities resolve when subjects recover.

Program Area: MOOD DISORDERS\Bipolar

Search Again