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 Project Summary  Carolyn M. Salafia, M.D. (Young Investigator 2003) of Columbia University, is investigating the role of abnormalities of the placenta in subjects who later developed schizophrenia. Previous work suggests that intrauterine risk factors may influence the likelihood of schizophrenia, including several risk factors that are directly related to placental function. Previously collected measures of placental growth and development will be related to risk of schizophrenia in members of a large birth cohort. It is hypothesized that schizophrenia risk will be related to poor placental growth, a key determinant of fetal oxygen and nutrient availability, and that the more severe the abnormal placental growth, the stronger the associations with schizophrenia. Program Area: SCHIZOPHRENIA/PSYCHOTIC DISORDERS\Schizophrenia |
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Mei Huang, Ph.D., Vanderbilt University Medical Center, 2005 & 2007 Young Investigator