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 Project Summary  Kenji Tanaka, M.D., Ph.D. (Young Investigator 2007) of Columbia University, will explore the neurobiology of obsessive-compulsive disorder (OCD) and the role of serotonin. OCD is characterized by a particular set of behaviors, but knowledge of the exact functional abnormality remains unclear because valid animal models are lacking. Dr. Tanaka’s laboratory will develop mouse models, and will also test Dr. Tanaka’s hypothesis that increased signaling by a receptor for the neurotransmitter serotonin in the striatum region of the brain leads to compulsive behavior. Program Area: ANXIETY DISORDERS\Obsessive Compulsive Disorder (OCD) |
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Mei Huang, Ph.D., Vanderbilt University Medical Center, 2005 & 2007 Young Investigator