A faculty member of the University of Maryland since the 1970s, Dr. Schwarcz’ early research focused on molecular and cellular mechanisms underlying neurodegenerative and seizure disorders. He identified a critical role of endogenous neurotoxic agents related to the neurotransmitter glutamate and pioneered the idea that specific anti-glutamatergic interventions can prevent nerve cell death. Such neuroprotective strategies may combat catastrophic brain diseases such as Huntington’s disease, Alzheimer’s disease, and stroke. More recently, Dr. Schwarcz turned his attention to biological psychiatry, showing that several metabolites of the amino acid tryptophan are substantively involved in the pathophysiology of diseases ranging from major depression to schizophrenia. He and his colleagues are currently exploiting this concept to develop biomarkers and pharmacological treatments.

Dr. Schwarcz received his bachelor’s degree in chemistry as well as his Ph.D. in biochemistry from the University of Vienna, Austria. He has been a faculty